2-[2-(4-甲氧基苯基)乙基]苯甲酸合成路线 (共 8 条)
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; P=760.051 Torr; 5 h;
参考文献
EP1408033 A1, ;
Page 110 ;
反应条件
hydrogen; triethylamine in ethanol T=80°C; P=7600.51 Torr; 2.5 h;
参考文献
EP1408033 A1, ;
Page 111 ;
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=2844.3 - 3102.9 Torr; 5 h;
参考文献
Mali, Raghao S.; Shelke, Dattatray W.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 8 p. 822 - 825
反应条件
1: 1.) t-BuOK / 1.) t-BuOH, ether, 20 deg C, 30 min, 2.) t-BuOH, ether, THF, 3 h 2: 79 percent / H2 / 10percent Pd/C / ethyl acetate / 5 h / 2844.3 - 3102.9 Torr View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 32, # 8 p. 822 - 825
反应条件
sodium hydroxide; sodium amalgam
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 29, p. 776 - 794
反应条件
1: aq. KOH 2: Na-Hg, aq. NaOH View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 29, p. 776 - 794
反应条件
phosphorus pentoxide in xylene Heating;
参考文献
Dhainaut, Alain; Regnier, Gilbert; Atassi, Ghanem; Pierre, Alain; Leonce, Stephane; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 13 p. 2481 - 2496
反应条件
boron trifluoride diethyl etherate; trifluoroacetic anhydride in dichloromethane T=20°C; 5 h;
参考文献
Ube Industries, Ltd.
Patent: EP1408033 A1, 2004 ;
Location in patent: Page 110 ;