5,6,7,8-四氢-5-氧代咪唑并[1,5-c]嘧啶合成路线 （共 8 条）
反应条件
in N,N-dimethyl-formamide T=20 - 70°C; 21 h;
参考文献
Maier, Udo; Grauert, Matthias; Hoffmann, Matthias; Hoenke, Christoph; Joergensen, Anne T.; Pautsch, Alexander; Brandl, Trixi; Breitfelder, Steffen; Scheuerer, Stefan; Erb, Klaus; Pieper, Michael; Pragst, Ingo
Patent: US2007/259855 A1, 2007 ;
Location in patent: Page/Page column 20 ;
反应条件
in N,N-dimethyl-formamide T=70°C; 7 h;
参考文献
El-Naggar, Mohamed; Piggott, Andrew M.; Capon, Robert J.
Organic Letters, 2008 , vol. 10, # 19 p. 4247 - 4250
反应条件
in dichloromethane T=22°C; Heating / reflux;
参考文献
WO2007/9757 A1, ;
Page/Page column 39 ;
WO 2007/009757 A1
反应条件
in chloroform 24 h; Heating;
参考文献
Jairam, Rick; Potvin, Pierre G.
Journal of Organic Chemistry, 1992 , vol. 57, # 15 p. 4136 - 4141
反应条件
in chloroform 2 h; Heating;
参考文献
Potvin, Pierre G.; Wong, Man Hung
Journal of the Chemical Society, Chemical Communications, 1987 , p. 672 - 674
参考文献
Monatshefte fuer Chemie, , vol. 87, p. 679,690
反应条件
1: 75 percent / dimethylformamide / 10 h
2: 95 percent / hydrochloric acid / 10 h / Heating
View Scheme
参考文献
Arcari; Bernardi; Cimaschi; Falconi; Luini; Scarponi
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 p. 1467 - 1471
反应条件
1: dimethylformamide / Heating
2: 2.5 g / 5 M HCl / Heating
3: 2.51 g / conc. HCl / 75 °C
View Scheme
参考文献
Arcari; Bernardi; Cimaschi; Falconi; Luini; Scarponi
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 p. 1467 - 1471
