sodium hydride; methyl malonic acid diethylester in N,N-dimethyl-formamide T=20°C; 0.0833333 h;

in N,N-dimethyl-formamide T=2130°C; 24 h; Overall yield = 60 percent; chemoselective reaction;

1: methyl malonic acid diethylester With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0 - 20°C; 0.166667 h; 2: (2,5-dimethylphenyl)(phenyl)iodonium triflate in N,N-dimethyl-formamide; mineral oil T=0 - 20°C; Overall yield = 95 percent; chemoselective reaction;

1: 3-methoxy-phenol With potassium tert-butylate in tetrahydrofuran T=0°C; 0.25 h; 2: (2,5-dimethylphenyl)(phenyl)iodonium triflate in tetrahydrofuran T=40°C; Overall yield = > 99 percent; chemoselective reaction;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '608317', constants.ctx, '0')">m-chloroperbenzoic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=20&deg;C;&nbsp;3&nbsp;h;&nbsp;<br /> &nbsp;

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '1813600', constants.ctx, '0')">trifluoromethylsulfonic anhydride</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3680414', constants.ctx, '0')">urea hydrogen peroxide addition compound</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1733203', constants.ctx, '0')">2,2,2-trifluoroethanol</a> <br />T=0&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '1446140', constants.ctx, '0')">iodobenzene</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1733203', constants.ctx, '0')">2,2,2-trifluoroethanol</a> <br />T=0&deg;C;&nbsp;<br />Stage #3: <a href="#" onclick="return RXDsubstances(event, this, '1901563', constants.ctx, '0')">para-xylene</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1733203', constants.ctx, '0')">2,2,2-trifluoroethanol</a> <br />T=0 - 20&deg;C;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '608317', constants.ctx, '0')">3-chloro-benzenecarboperoxoic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=20&deg;C;&nbsp;5&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 64 percent / 0.25 h / Ambient temperature<br />2: 67 percent / H₂O₂ / ethanol; H₂O / Heating<br /> <br /> &nbsp;

&nbsp;1.) CH₂Cl₂, r.t., 1 h; 2.) CH₂Cl₂, r.t., 0.5 h;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;