1: 1,6-heptadien-4-ol With sodium hydride in tetrahydrofuran 2 h; 2: benzyl bromide With tetra-(n-butyl)ammonium iodide in tetrahydrofuran Cooling;

1: With chlorosulphonyl isocyanate; sodium carbonate in dichloromethane 20 h; Heating; 2: With sodium hydroxide in methanol T=20°C; 1 h;

1.1: bis-(1,2-dimethylpropyl)borane / tetrahydrofuran / 0 - 20 °C / |Inert atmosphere 1.2: 50 °C 2.1: palladium hydroxide on carbon; hydrogen / methanol / 760.05 Torr View Scheme