(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
carrot (Daucus carota, root); [14C]-Chloramphenicol in ethanol; water T=25°C; 72 h;
参考文献
Balakrishnan, Umesh; Ananthi, Nallamuthu; Selvan, Sakthivel Tamil; Pal, Ravindra; Ariga, Katsuhiko; Velmathi, Sivan; Vinu, Ajayan
Chemistry - An Asian Journal, 2010 , vol. 5, # 4 p. 897 - 903
反应条件
1: With benzo[1,3,2]dioxaborole; rhodium-complex in water; toluene T=20°C; 2 h; 2: With sodium hydroxide; ethanol; dihydrogen peroxide in water; toluene T=0 - 20°C; 2.5 h;
参考文献
CARREIRA, Erick M.; Sumitomo Chemical Company, Limited
Patent: US2005/277772 A1, 2005 ;
Location in patent: Page/Page column 24 ;
反应条件
dimethylsulfide borane complex; diphenyl-N-(3-pyridylmethyl)prolinol N-oxide in tetrahydrofuran 5 h; Heating;
参考文献
O'Neil, Ian A.; Turner, Carl D.; Kalindjian, S. Barret
Synlett, 1997 , vol. 1997, # 7 p. 777 - 780
反应条件
RuCl2[(R)-binap][(R,R)-dpen]; potassium tert-butylate; hydrogen in isopropyl alcohol T=26 - 30°C; P=3040 Torr; 2 h;
参考文献
Ohkuma; Koizumi; Doucet; Pham; Kozawa; Murata; Katayama; Yokozawa; Ikariya; Noyori
Journal of the American Chemical Society, 1998 , vol. 120, # 51 p. 13529 - 13530
反应条件
toluene-4-sulfonic acid in methanol 0.5 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
European Journal of Inorganic Chemistry, , # 6 p. 783 - 788
反应条件
3 A molecular sieve; oxygen; sodium carbonate; Pd((-)-sparteine)2Cl2 in tert-butyl alcohol T=65°C; 32 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 19 p. 7535 - 7537
反应条件
1: With titanium(IV) isopropylate; (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol in diethyl ether; toluene T=0°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in diethyl ether; water; toluene Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Fernandez-Mateos, Emilio; MacIa, Beatriz; Yus, Miguel
Tetrahedron Asymmetry, 2012 , vol. 23, # 10 p. 789 - 794
反应条件
1: With (S)-N-(3-methyl-1-(1-pyrrolidin-1-yl)butan-2-yl) diphenylphosphinic amideamine in hexane T=20°C; 2 h; Inert atmosphere; 2: With ammonium chloride in hexane; water T=0°C; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Baker-Salisbury, Mollie G.; Starkman, Brian S.; Frisenda, Gabrielle M.; Roteta, Leslie A.; Tanski, Joseph M.
Inorganica Chimica Acta, 2014 , vol. 409, # PART B p. 394 - 398
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol T=20°C; 11 h;
参考文献
Hayashi; Hirate; Kitayama; Tsuji; Torii; Uozumi
Journal of Organic Chemistry, 2001 , vol. 66, # 4 p. 1441 - 1449
反应条件
potassium phosphate; Novozym 435; (CO)2ClRu(benzyloxytetraphenylpentadienyl) in toluene T=25°C; 20 h;
参考文献
Organic Letters, , vol. 7, # 20 p. 4523 - 4526
