2-(2-氯苯基)-2-(4,5-二氢噻吩并[2,3-C]吡啶-6(7H)-基)乙酸甲酯合成路线 (共 8 条)
反应条件
1: 2-chloro-α-methoxycarbonylbenzyl bromide With potassium carbonate in methanol; water T=25°C; 0.166667 h; 2: 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine in methanol; water T=60 - 65°C; 6 h;
参考文献
Reddy, K. Tatendra; Kumar, K. Suneel; Omprakash; Dubey
Synthetic Communications, 2013 , vol. 43, # 10 p. 1387 - 1396
反应条件
hydrogenchloride in water T=25 - 55°C;
参考文献
Reddy, K. Tatendra; Kumar, K. Suneel; Omprakash; Dubey
Synthetic Communications, 2013 , vol. 43, # 10 p. 1387 - 1396
反应条件
1.1: sulfuric acid / 3 h / |Reflux 2.1: potassium carbonate / methanol; water / 0.17 h / 25 °C 2.2: 6 h / 60 - 65 °C View Scheme
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1387 - 1396
反应条件
1: triethylamine / acetonitrile / |Reflux 2: hydrogenchloride / water / 25 - 55 °C View Scheme
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1387 - 1396
反应条件
1: triethylamine / acetonitrile / |Reflux 2: hydrogenchloride / water / 25 - 55 °C View Scheme
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1387 - 1396
反应条件
1: sodium hydrogencarbonate / methanol / 10 °C / |Reflux 2: hydrogenchloride / water / 25 - 55 °C View Scheme
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1387 - 1396
反应条件
1.1: hydrogenchloride / water / 0.5 h / 80 - 85 °C 1.2: 20 °C 2.1: potassium carbonate / methanol; water / 0.17 h / 25 °C 2.2: 6 h / 60 - 65 °C View Scheme
参考文献
Synthetic Communications, , vol. 43, # 10 p. 1387 - 1396
反应条件
hydrogenchloride in water; acetone T=25°C;
参考文献
Reddy, K. Tatendra; Kumar, K. Suneel; Omprakash; Dubey
Synthetic Communications, 2013 , vol. 43, # 10 p. 1387 - 1396