3-苯基异恶唑-5-羧酸合成路线 (共 28 条)
反应条件
1: With sodium hydroxide; water in 1,4-dioxane 0.5 - 16 h; 2: With hydrogenchloride in water pH=4;
参考文献
VICURON PHARMACEUTICALS INC.
Patent: US2006/211603 A1, 2006 ;
Location in patent: Page/Page column 39; 48 ;
参考文献
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <8> 13, p. 39,40
反应条件
jones reagent in acetone T=0 - 35°C; 3.5 h;
参考文献
Wang, Xi-Zhao; Jia, Jiong; Zhang, Yan; Xu, Wei-Ren; Liu, Wei; Shi, Fang-Niu; Wang, Jian-Wu
Journal of the Chinese Chemical Society, 2007 , vol. 54, # 3 p. 643 - 652
反应条件
2-nitrobenzeneboronic acid in 1,2-dichloro-ethane T=25°C; 2 h; Inert atmosphere; regioselective reaction;
参考文献
Zheng, Hongchao; McDonald, Robert; Hall, Dennis G.
Chemistry - A European Journal, 2010 , vol. 16, # 18 p. 5454 - 5460
反应条件
1: 85 percent / tetrahydrofuran / 2 h / Ambient temperature 2: 95 percent / dil. HCl View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 21 p. 2193 - 2194
参考文献
Horikawa, Hiroshi; Nishitani, Takashi; Iwasaki, Tameo; Inoue, Ichizo
Tetrahedron Letters, 1983 , vol. 24, # 21 p. 2193 - 2194
反应条件
1: water / Eintragen von wss. Natronlauge unter starker Kuehlung 2: aq.-ethanolic NaOH View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 76, p. 148,163
反应条件
in diethyl ether 24 h; Ambient temperature;
参考文献
Baranski, Andrzej
Polish Journal of Chemistry, 1982 , vol. 56, # 2 p. 257 - 266
反应条件
potassium permanganate in acetone
参考文献
Zhurnal Organicheskoi Khimii, , vol. 3, p. 821 - 826,789 - 793
反应条件
potassium permanganate in acetone
参考文献
Gazzetta Chimica Italiana, , vol. 98, p. 74 - 84