2,2,4-三甲基-1,3-戊二醇合成路线 （共 62 条）
反应条件
1: hydrobromic acid / 70 - 80 °C
2: silver acetate; glacial acetic acid / Verseifung das Diacetat
View Scheme
参考文献
Mossler
Monatshefte fuer Chemie, 1903 , vol. 24, p. 599,607, 609
反应条件
1-methyl-1H-imidazole; [Cu(MeCN)]4*CF3SO3; 4,4'-dimethoxy-2,2'-bipyridine; ABNO; oxygen in acetonitrile
T=20°C; 0.5 h;
参考文献
Steves, Janelle E.; Stahl, Shannon S.
Journal of the American Chemical Society, 2013 , vol. 135, # 42 p. 15742 - 15745
反应条件
Fe(2+)*C12H13N3*2CF3O3S(1-); dihydrogen peroxide in water; acetonitrile
T=20°C; 0.25 h; chemoselective reaction;
参考文献
Lenze, Matthew; Bauer, Eike B.
Chemical Communications, 2013 , vol. 49, # 52 p. 5889 - 5891
反应条件
1: TsOH*H2O / CHCl3
2: 500 °C
3: aq. NaOH / methanol
View Scheme
参考文献
Schwenk,U.; Becker,A.
Justus Liebigs Annalen der Chemie, 1972 , vol. 756, p. 162 - 169
反应条件
phosphoric acid; boron trifluoride diethyl etherate in dichloromethane
参考文献
Jung,M.E.; Speltz,L.M.
Journal of the American Chemical Society, 1976 , vol. 98, p. 7882 - 7884
反应条件
(i) BF3-Et2O, H3PO4, CH2Cl2, (ii) pyridinium chlorochromate; Multistep reaction;
参考文献
Jung,M.E.; Speltz,L.M.
Journal of the American Chemical Society, 1976 , vol. 98, p. 7882 - 7884
反应条件
toluene-4-sulfonic acid in tetrahydrofuran
3 h; RefluxMolecular sieve;
参考文献
EASTMAN CHEMICAL COMPANY
Patent: WO2012/82348 A1, 2012 ;
Location in patent: Page/Page column 25 ;
反应条件
hydrogen bromide
T=70 - 80°C; 15 h;
参考文献
Wilcox,C.F.; Nealy,D.L.
Journal of Organic Chemistry, 1963 , vol. 28, p. 3454 - 3457
反应条件
toluene-4-sulfonic acid in chloroform
参考文献
Schwenk,U.; Becker,A.
Justus Liebigs Annalen der Chemie, 1972 , vol. 756, p. 162 - 169
反应条件
bismuth trifluoromethanesulphonate in acetonitrile
T=20°C; 1 h;
参考文献
Carrigan; Freiberg; Smith; Zerth; Mohan
Synthesis, 2001 , # 14 p. 2091 - 2094
