3,5-二-叔丁基苯甲酰氯合成路线 （共 7 条）
反应条件
in thionyl chloride; toluene
参考文献
BP Corporation North America Inc.
Patent: EP1157047 B1, 2003 ;
反应条件
1: 1.) LiBu / 1.) THF, ether, -78 deg C, 3 h, 2.) THF, -78 deg C to RT 2: SOCl2 / Heating View Scheme
参考文献
Alberti, Angelo; Benaglia, Massimo
Journal of Organometallic Chemistry, 1992 , vol. 434, # 2 p. 151 - 158
反应条件
thionyl chloride 1) pyridin, 2) heating; Multistep reaction;
参考文献
Adiwidjaja, Gunadi; Guenther, Horst; Voss, Juergen
Angewandte Chemie, 1980 , vol. 92, # 7 p. 559 - 561
反应条件
hydrogen; palladium on barium sulfate in xylene
参考文献
Wrigglesworth, Roger; Walpole, Christopher S. J.; Bevan, Stuart; Campbell, Elizabeth A.; Dray, Andy; Hughes, Glyn A.; James, Iain; Masdin, Kay J.; Winter, Janet
Journal of Medicinal Chemistry, 1996 , vol. 39, # 25 p. 4942 - 4951
反应条件
diethyl ether; ethanol; Ethoxymagnesiummalonsaeure-diethylester
anschl. mit Essigsaeure, H2O und H2SO4;
参考文献
Reichardt, Christian; Loebbecke, Stefan; Mehranpour, Abdol Mohammed; Schaefer, Gerhard
Canadian Journal of Chemistry, 1998 , vol. 76, # 6 p. 686 - 694
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
3 h; Ambient temperature;
参考文献
Wrigglesworth, Roger; Walpole, Christopher S. J.; Bevan, Stuart; Campbell, Elizabeth A.; Dray, Andy; Hughes, Glyn A.; James, Iain; Masdin, Kay J.; Winter, Janet
Journal of Medicinal Chemistry, 1996 , vol. 39, # 25 p. 4942 - 4951
反应条件
1: meso-lt;4-(trimethylsilylethynyl)phenylgt;dipyrromethane With ethylmagnesium bromide in tetrahydrofuran; toluene
T=20°C; 0.5 h;
2: 3,5-di-tert-butylbenzoyl chloride in toluene
T=20°C; 0.666667 h;
参考文献
Yu, Lianhe; Lindsey, Jonathan S
Tetrahedron, 2001 , vol. 57, # 45 p. 9285 - 9298
