烯丙基-(3-苯基-2-丙炔)基丙二酸二乙酯合成路线 （共 5 条）
反应条件
N,O-bis-(trimethylsilyl)-acetamide; 1,4-di(diphenylphosphino)-butane; tris-(dibenzylideneacetone)dipalladium(0) in toluene T=110°C; 1 h;
参考文献
Jeong; Seong Deok Seo; Jin Young Shin
Journal of the American Chemical Society, 2000 , vol. 122, # 41 p. 10220 - 10221
反应条件
1: diethyl 2-allyl-malonate With sodium hydride in tetrahydrofuran T=20°C; 2: 1-(3-bromo-1-propynyl)benzene in tetrahydrofuran T=20°C; 12 h; Further stages.;
参考文献
Morimoto, Tsumoru; Fuji, Koji; Tsutsumi, Ken; Kakiuchi, Kiyomi
Journal of the American Chemical Society, 2002 , vol. 124, # 15 p. 3806 - 3807
反应条件
water; triethylamine; PS-PEG resin supported bisphosphine-palladium complex Sonogashira coupling; 1.5 h; Heating;
参考文献
Nakai, Yasushi; Kimura, Tsutomu; Uozumi, Yasuhiro
Synlett, 2006 , # 18 p. 3065 - 3068
反应条件
1: diethyl 2-allyl-malonate With sodium hydride in tetrahydrofuran T=20°C; 1 h; 2: 3-phenyl-2-propynol methanesulfonate (ester) in tetrahydrofuran T=20°C;
参考文献
Kobayashi, Toshitake; Koga, Yuji; Narasaka, Koichi
Journal of Organometallic Chemistry, 2001 , vol. 624, # 1-2 p. 73 - 87
反应条件
1.1: Et3N / CH2Cl2 / 0.5 h / 20 °C 2.1: NaH / tetrahydrofuran / 1 h / 20 °C 2.2: tetrahydrofuran / 20 °C View Scheme
参考文献
Kobayashi, Toshitake; Koga, Yuji; Narasaka, Koichi
Journal of Organometallic Chemistry, 2001 , vol. 624, # 1-2 p. 73 - 87
