1,2-二氯-4-氟苯合成路线

参考文献

Barton, Patrick; Brough, Steven; Evans, Richard; Luckhurst, Christopher A.; Mochel, Tobias; Perry, Matthew W. D.; Rigby, Aaron; Sanganee, Hitesh; Sisson, Adam; Springthorpe, Brian; Bahl, Ash; Bowers, Keith; Riley, Robert J.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6688 - 6693,6

1435-49-01,2-二氯-4-氟苯

13656-52-54,5-二氯-2-氟苯磺酰氯

参考文献

Yakobson,G.G. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, # 1 p. 163 - 170,149 - 155

1435-49-01,2-二氯-4-氟苯

2339-78-81,2-二氯-4-氟-5-硝基苯

参考文献

Finger et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97

1435-49-01,2-二氯-4-氟苯+

91419-52-2N-Boc-4-氰基哌啶

669068-10-41-N-Boc-4-(3,4-二氯苯基)-4-氰基哌啶

参考文献

ABBVIE INC.; BAYBURT, Erol K.; CLAPHAM, Bruce; COX, Phil B.; DAANEN, Jerome F.; GOMTSYAN, Arthur; KORT, Michael E.; KYM, Philip R.; VOIGHT, Eric A.; SCHMIDT, Robert G.; DART, Michael J.; GFESSER, Gregory
Patent: WO2013/62966 A2, 2013 ;
Location in patent: Paragraph 254; 255 ;

1435-49-01,2-二氯-4-氟苯+

77-78-1硫酸二甲酯

890524-58-03,4-二氯-2-甲基氟苯

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ASTRAZENECA AB
Patent: WO2006/62476 A1, 2006 ;
Location in patent: Page/Page column 3-4 ;
WO 2006/062476 A1

1435-49-01,2-二氯-4-氟苯+

93-61-8甲基甲酰苯胺

95399-95-42,3-二氯-6-氟苯甲醛

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Fisons plc
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