2-(2-N-Boc-氨基乙基)吡啶合成路线 （共 3 条）
反应条件
in tetrahydrofuran T=0 - 20°C; 3.5 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1424336 A1, 2004 ;
Location in patent: Page 163 ;
反应条件
1: 1.) sodium hydride / 1.) THF, 0 deg C, 15 min, 2.) THF, RT, 2 h 2: HCl / dioxane / 0.5 h / 40 °C View Scheme
参考文献
Kempf, Dale J.; Codacovi, Lynnmarie; Wang, Xiu Chun; Kohlbrenner, William E.; Wideburg, Norman E.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 320 - 330
反应条件
platinum(IV) oxide; hydrogen in acetic acid
T=80°C; P=6205.94 Torr; 0.666667 h; Microwave irradiation;
参考文献
Piras, Leonarda; Genesio, Eva; Ghiron, Chiara; Taddei, Maurizio
Synlett, 2008 , # 8 p. 1125 - 1128
