1’-表2’,2’-二氟-2’-脱氧尿苷3',5'-二苯甲酸酯合成路线 (共 2 条)
反应条件
tin(IV) chloride in 1,2-dichloro-ethane T=20 - 83°C; 22 h; Product distribution / selectivity;
参考文献
SICOR INC.
Patent: WO2006/63105 A1, 2006 ;
Location in patent: Page/Page column 11-12 ;
反应条件
trimethylsilyl trifluoromethanesulfonate in 1,2-dichloro-ethane T=83°C; 17 h; Product distribution / selectivity;
参考文献
Chou; Heath; Patterson; Poteet; Lakin; Hunt
Synthesis, 1992 , # 6 p. 565 - 570