1-甲氧基-4-(2-苯基乙基)-苯合成路线 （共 58 条）
反应条件
1: S2O8(2-), HClO4 / Cu(ClO4)2 / acetonitrile; H2O / 0.42 h / 83 °C / other reaction conditions, other substrate 2: pyridine-chlorochromate View Scheme
参考文献
Camaioni, Donald M.; Franz, James A.
Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1607 - 1613
反应条件
10 Pd on charcoal; diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate in ethanol
4 h; Reflux;
参考文献
Liu, Qiang; Li, Jing; Shen, Xiao-Xia; Xing, Rui-Guang; Yang, Jie; Liu, Zhengang; Zhou, Bo
Tetrahedron Letters, 2009 , vol. 50, # 9 p. 1026 - 1028
反应条件
1: With sodium acetate in N,N-dimethyl acetamide
T=100°C; Heck reaction; Inert atmosphere;
2: With hydrogen in N,N-dimethyl acetamide
T=20°C; P=760.051 Torr;
参考文献
Kantam, M. Lakshmi; Chakravarti, Rajashree; Chintareddy, Venkat Reddy; Sreedhar; Bhargava, Suresh
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2544 - 2550
反应条件
1: With sodium acetate in N,N-dimethyl acetamide
T=100°C; Heck reaction; Inert atmosphere;
2: With hydrogen in N,N-dimethyl acetamide
T=20°C; P=760.051 Torr;
参考文献
Kantam, M. Lakshmi; Chakravarti, Rajashree; Chintareddy, Venkat Reddy; Sreedhar; Bhargava, Suresh
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 16 p. 2544 - 2550
反应条件
sodium methylate; triphenylphosphine; palladium diacetate in methanol
T=25°C; 48 h;
参考文献
Wei, Li-Lan; Wei, Li-Mei; Pan, Wen-Bin; Leou, Shiow-Piaw; Wu, Ming-Jung
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1979 - 1981
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium carbonate in tetrahydrofuran; water
T=80°C; Suzuki-Miyaura Coupling; 48 h; Inert atmosphereSealed tube;
参考文献
St. Denis, Jeffrey D.; Scully, Conor C. G.; Lee, C. Frank; Yudin, Andrei K.
Organic Letters, 2014 , vol. 16, # 5 p. 1338 - 1341
反应条件
palladium diacetate; potassium carbonate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in water; toluene
T=80°C; Suzuki-Miyaura cross-coupling; 24 h;
参考文献
Dreher, Spencer D.; Lim, Siang-Ee; Sandrock, Deidre L.; Molander, Gary A.
Journal of Organic Chemistry, 2009 , vol. 74, # 10 p. 3626 - 3631
反应条件
N,N,N',N,-tetramethylethylenediamine; ((Me)N2N)Ni-Cl in tetrahydrofuran
T=20°C; Kumada-Corriu-Tamao coupling reaction; 2 h; Inert atmosphere;
参考文献
Vechorkin, Oleg; Proust, Valerie; Hu, Xile
Journal of the American Chemical Society, 2009 , vol. 131, # 28 p. 9756 - 9766
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium carbonate in tetrahydrofuran; water
T=80°C; Suzuki-Miyaura Coupling; 90 h; Inert atmosphereSealed tube;
参考文献
St. Denis, Jeffrey D.; Scully, Conor C. G.; Lee, C. Frank; Yudin, Andrei K.
Organic Letters, 2014 , vol. 16, # 5 p. 1338 - 1341
反应条件
1: (4-methoxyphenyl)methanol With n-butyllithium in tetrahydrofuran
2: With methyl iodide in tetrahydrofuran
T=20°C; 1 h;
3: benzyl-magnesium bromide in tetrahydrofuran
T=20°C; 1 h;
参考文献
Shintou, Taichi; Kikuchi, Wataru; Mukaiyama, Teruaki
Chemistry Letters, 2003 , vol. 32, # 8 p. 676 - 677
