boron trifluoride diethyl etherate; sodium iodide in acetonitrile T=25°C; 0.5 h;

1: With palladium diacetate; 1,3-bis-(diphenylphosphino)propane; potassium carbonate in water; dimethyl sulfoxide T=80°C; Sonogashira coupling; 40 h; 2: With hydrogenchloride in dimethyl sulfoxide T=20°C; 0.5 h;