palladium 10 on activated carbon; hydrogen in tetrahydrofuran; hexane P=3750.38 Torr; 2 h;

palladium 10 on activated carbon; hydrogen in tetrahydrofuran; hexane P=3750.38 Torr; 2 h;

palladium 10 on activated carbon; hydrogen in tetrahydrofuran; hexane P=3750.38 Torr; 2 h;

1: dicyclohexylcarbodiimide, DMAP / CH2Cl2 / 12 h / Ambient temperature 2: 88 percent / BCl3 / CH2Cl2 / 0.5 h / -78 - -40 °C 3: 1.) Et3N, 2.) H2O / 1.) CH2Cl2, 0-5 deg C, 2.) 30 min 4: ethanol; CHCl3 / 70 - 80 °C View Scheme

1: dicyclohexylcarbodiimide, DMAP / CH2Cl2 / 12 h / Ambient temperature 2: 98 percent / BCl3 / CH2Cl2 / 0.5 h / -78 - -40 °C View Scheme