1-[1-(2-氯苯基)-2-二甲基氨基乙基]环己烷-1-醇合成路线 (共 3 条)
反应条件
1: 1.) (COCl)2, DMF / 1.) CH2Cl2, RT, 4 h 2: lithium diisopropylamide / -78 °C 3: borane or AlH3 / tetrahydrofuran View Scheme
参考文献
Yardley; Morris Husbands; Stack; Butch; Bicksler; Moyer; Muth; Andree; Fletcher III; James; Sielecki
Journal of Medicinal Chemistry, 1990 , vol. 33, # 10 p. 2899 - 2905
反应条件
1: lithium diisopropylamide / -78 °C 2: borane or AlH3 / tetrahydrofuran View Scheme
参考文献
Yardley; Morris Husbands; Stack; Butch; Bicksler; Moyer; Muth; Andree; Fletcher III; James; Sielecki
Journal of Medicinal Chemistry, 1990 , vol. 33, # 10 p. 2899 - 2905
反应条件
1: lithium diisopropylamide / -78 °C 2: borane or AlH3 / tetrahydrofuran View Scheme
参考文献
Yardley; Morris Husbands; Stack; Butch; Bicksler; Moyer; Muth; Andree; Fletcher III; James; Sielecki
Journal of Medicinal Chemistry, 1990 , vol. 33, # 10 p. 2899 - 2905