(R)-(-)-N-苯甲基-2-苯基甘氨酸醇合成路线 (共 32 条)
反应条件
1: (R)-2-Phenyl-2-{[1-phenyl-meth-(Z)-ylidene]-amino}-ethanol With samarium; trimethylaluminum in hexane T=0°C; 2: allyl bromide in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Yanada; Okaniwa; Kaieda; Ibuka; Takemoto
Journal of Organic Chemistry, 2001 , vol. 66, # 4 p. 1283 - 1286
反应条件
1: aq. NaOH / 1 h / 20 °C 2: LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 13 p. 4343 - 4354
反应条件
sodium tetrahydroborate in methanol Reduction; 22 h;
参考文献
Synthesis, , # 8 p. 1170 - 1179
反应条件
1: methanol / 1 h 2: NaBH4 / methanol / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 20 p. 6423 - 6426
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in toluene 1 h; Ambient temperature;
参考文献
Agami; Couty; Hamon; Prince; Puchot
Tetrahedron, 1990 , vol. 46, # 20 p. 7003 - 7010
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 8 h; Heating;
参考文献
Coeffard, Vincent; Thobie-Gautier, Christine; Beaudet, Isabelle; Le Grognec, Erwan; Quintard, Jean-Paul
European Journal of Organic Chemistry, 2008 , # 2 p. 383 - 391
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating;
参考文献
Journal of the American Chemical Society, , vol. 126, # 13 p. 4343 - 4354
反应条件
1: aq. NaOH / 1 h / 20 °C 2: LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 13 p. 4343 - 4354
反应条件
sodium tetrahydroborate in methanol 20 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 40, # 15 p. 2935 - 2938
反应条件
sodium carbonate T=110°C; 12 h; Inert atmosphere;
参考文献
Aydemir, Murat; Durap, Feyyaz; Kayan, Cezmi; Baysal, Akin; Turgut, Ylmaz
Synlett, 2012 , vol. 23, # 19 art. no. ST-2012-D0604-L, p. 2777 - 2784