1: in acetic acid T=70°C; 1 h; 2: With sulfuric acid in acetic acid T=70°C; 1 h;

1: With sodium acetate; acetic acid T=70°C; 3 h; 2: With sulfuric acid T=70°C; 3 h; 3: With sodium acetate in water

1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; caesium carbonate; copper(l) chloride in N,N-dimethyl-formamide T=80°C; Suzuki coupling; 2 h; Inert atmosphere;

1: N-bromosuccinmide / acetonitrile / 3 h / 0 °C 2: dichloromethane / 3 h / 25 °C 3: potassium carbonate / tetrahydrofuran / 0 °C 4: methanol / 8 h / Reflux 5: sodium tetrahydroborate / tetrahydrofuran / 10 h / Reflux 6: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 7: pyridine / acetone / 10 h / 20 °C / Inert atmosphere; UV-irradiation 8: anhydrous magnesium perchlorate / acetonitrile / 3 h / 60 °C 9: water; potassium carbonate / methanol / 15 h / Reflux View Scheme

1: dichloromethane / 3 h / 25 °C 2: potassium carbonate / tetrahydrofuran / 0 °C 3: methanol / 8 h / Reflux 4: sodium tetrahydroborate / tetrahydrofuran / 10 h / Reflux 5: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 6: pyridine / acetone / 10 h / 20 °C / Inert atmosphere; UV-irradiation 7: anhydrous magnesium perchlorate / acetonitrile / 3 h / 60 °C 8: water; potassium carbonate / methanol / 15 h / Reflux View Scheme

1: pyridine / acetone / 10 h / 20 °C / Inert atmosphere; UV-irradiation 2: anhydrous magnesium perchlorate / acetonitrile / 3 h / 60 °C 3: water; potassium carbonate / methanol / 15 h / Reflux View Scheme

1: methanol / 8 h / Reflux 2: sodium tetrahydroborate / tetrahydrofuran / 10 h / Reflux 3: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 4: pyridine / acetone / 10 h / 20 °C / Inert atmosphere; UV-irradiation 5: anhydrous magnesium perchlorate / acetonitrile / 3 h / 60 °C 6: water; potassium carbonate / methanol / 15 h / Reflux View Scheme

1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 4 h / 20 °C 2: pyridine / acetone / 10 h / 20 °C / Inert atmosphere; UV-irradiation 3: anhydrous magnesium perchlorate / acetonitrile / 3 h / 60 °C 4: water; potassium carbonate / methanol / 15 h / Reflux View Scheme

1: iodine; silver trifluoromethanesulfonate / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere 2: 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; caesium carbonate; copper(l) chloride / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere View Scheme

1.1: acetic acid / methanol / 4 h / 25 °C / Inert atmosphere 2.1: ethanol / 14 h / 25 °C / Inert atmosphere 3.1: water; N,N-dimethyl-formamide / 4 h / 70 °C / Inert atmosphere 4.1: water; potassium hydroxide / methanol / 2 h / 100 °C / Inert atmosphere 4.2: 0 °C / pH 1 / Inert atmosphere 5.1: hydrogenchloride; thionyl chloride; benzotriazol-1-ol / 4 h / 0 - 25 °C / Inert atmosphere 6.1: iodine; silver trifluoromethanesulfonate / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere 7.1: 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; caesium carbonate; copper(l) chloride / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere View Scheme