1(1R,2R)-(+)-1-苯基亚丙基环氧合成路线 （共 69 条）
反应条件
Oxonereg;; potassium carbonate; acetic acid; chiral 1a-methyl-3-fluoro-3-methyldecal-2-one in ethylene glycol dimethyl ether; water T=25°C; pH=8.5 - 9; 6 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 24 p. 3891 - 3898
反应条件
chiral ruthenium porphyrin complex catalyst in toluene T=-10°C; 48 h; Title compound not separated from byproducts.;
参考文献
Organic Letters, , vol. 1, # 13 p. 2077 - 2080
反应条件
2-hydroxyethanethiol in glycerol T=26°C; pH=7.5; 0.916667 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 65, # 1-4 p. 41 - 48
反应条件
1: 75 percent / pyridine / CH2Cl2 / 16 h / 0 °C 2: 90 percent / MeONa / methanol / 1 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 21 p. 6019 - 6023
反应条件
1: 20 percent / ethanol; H2O / 16 h / 30 °C / bakers' yeast 2: 75 percent / pyridine / CH2Cl2 / 16 h / 0 °C 3: 90 percent / MeONa / methanol / 1 h / 0 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 21 p. 6019 - 6023
反应条件
pyridine; Oxonereg;; water-d2; sodium hydrogencarbonate; (S)-(-)-2-(diphenylmethyl)pyrrolidine in acetonitrile-D3 T=20°C; 4 h; Product distribution / selectivity;
参考文献
US2003/195366 A1, ;
Page/Page column 5 ;
反应条件
sodium hypochlorite; chiral (salen)Mn; (-)-N-benzylquininium chloride in chlorobenzene T=4°C; 10 h; other cis-olefins; other chiral quaternary ammonium salts; other Mn catalyst; other solvents; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 116, # 15 p. 6937 - 6938
反应条件
1: 48 h / Lactobacillus kefir 2: 68 percent / NaOEt / methanol / 0 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 5, # 7 p. 1249 - 1268
反应条件
1: 80 percent / SO2Cl2 / CCl4 / 40 °C 2: 48 h / Lactobacillus kefir 3: 68 percent / NaOEt / methanol / 0 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 5, # 7 p. 1249 - 1268
反应条件
1: 90 percent / 2N NaOH / H2O / Ambient temperature; pH ca. 7 2: 82.8 percent / pyridinium tosylate / benzene / 14 h / Heating 3: 80 percent / NaI / acetone / 1 h / 50 °C 4: 22 percent / Bu3SnH, AIBN / benzene / Heating 5: 85 percent / LiAlH4, AlCl3 / tetrahydrofuran / 1 h / -78 °C 6: 90 percent / methanol / 15 h / Ambient temperature 7: NaH / dioxane; dimethylformamide / 6 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 48, # 19 p. 3945 - 3960
