2-氧代吲哚啉-6-甲酸甲酯合成路线

334952-07-74-(甲氧基羰基)-2-硝基苯乙酸甲酯→14192-26-82-氧代吲哚啉-6-甲酸甲酯

参考文献

Roth, Gerald J.; Heckel, Armin; Colbatzky, Florian; Handschuh, Sandra; Kley, Joerg; Lehmann-Lintz, Thorsten; Lotz, Ralf; Tontsch-Grunt, Ulrike; Walter, Rainer; Hilberg, Frank
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4466 - 4480

1160293-27-52-[4-(甲氧羰基)-2-硝基苯基]丙二酸二甲酯→14192-26-82-氧代吲哚啉-6-甲酸甲酯

参考文献

WO2009/71523 A1, ;

Page/Page column 6; 17-18 ;

67-56-1甲醇+334952-09-96-羧基吲哚酮→14192-26-82-氧代吲哚啉-6-甲酸甲酯

参考文献

US2006/173183 A1, ;

Page/Page column 118-119 ;

14192-26-82-氧代吲哚啉-6-甲酸甲酯→334952-09-96-羧基吲哚酮

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2006/64044 A1, 2006 ;
Location in patent: Page/Page column 21-22 ;

14192-26-82-氧代吲哚啉-6-甲酸甲酯→656247-17-5尼达尼布

参考文献

WO2012/68441 A2, ;

108-24-7乙酸酐+14192-26-82-氧代吲哚啉-6-甲酸甲酯→676326-36-61-乙酰基-2,3-二氢-2-氧代-1H-吲哚-6-羧酸甲酯

参考文献

Roth, Gerald J.; Heckel, Armin; Colbatzky, Florian; Handschuh, Sandra; Kley, Joerg; Lehmann-Lintz, Thorsten; Lotz, Ralf; Tontsch-Grunt, Ulrike; Walter, Rainer; Hilberg, Frank
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4466 - 4480