反应条件
1: 2-(1H-Pyrazole-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane With sodium hydride in N,N-dimethyl-formamide
T=0°C; 1 h;
2: tert-butyl 3-[(methylsulfonyl)oxy]-1-azetidinecarboxylate in N,N-dimethyl-formamide
T=95°C; 5 h;
参考文献
Cui, J. Jean; Tran-Dube, Michelle; Shen, Hong; Nambu, Mitchell; Kung, Pei-Pei; Pairish, Mason; Jia, Lei; Meng, Jerry; Funk, Lee; Botrous, Iriny; McTigue, Michele; Grodsky, Neil; Ryan, Kevin; Padrique, Ellen; Alton, Gordon; Timofeevski, Sergei; Yamazaki, Shinji; Li, Qiuhua; Zou, Helen; Christensen, James; Mroczkowski, Barbara; Bender, Steve; Kania, Robert S.; Edwards, Martin P.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 18 p. 6342 - 6363
