2-氨基吡啶 N-氧化物合成路线 （共 34 条）
参考文献
Brown
Journal of the American Chemical Society, 1957 , vol. 79, p. 3565
反应条件
1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 20 °C / |Sealed tube 2: tetrahydroxydiboron / 0.17 h View Scheme
参考文献
Londregan, Allyn T.; Piotrowski, David W.; Xiao, Jun
Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-S0695-L, p. 2695 - 2700
反应条件
1: 2-aminopyridine-N-oxide With trifluoroacetic acid in dichloromethane 0.166667 h; 2: 4-nitro-phenylacetylene With dichloro(pyridine-2-carboxylato)gold(III) in dichloromethane T=40°C; 15 h; regioselective reaction;
参考文献
Talbot, Eric P. A.; Richardson, Melodie; McKenna, Jeffrey M.; Toste, F. Dean
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 4 p. 687 - 691
反应条件
1: concentrated sulfuric acid; peroxomonosulfuric acid 3: concentrated sulfuric acid; nitric acid View Scheme
参考文献
Brown
Journal of the American Chemical Society, 1957 , vol. 79, p. 3565
反应条件
potassium carbonate in N,N-dimethyl-formamide T=140°C; 5 h;
参考文献
Polish Journal of Chemistry, , vol. 72, # 11 p. 2378 - 2383
反应条件
1: 55 percent / KI / dimethylformamide / 3 h / Heating 2: 65 percent / PCl3 / ethyl acetate / 3 h / Heating 3: 76 percent / H2 / 10percent Pd/C / ethanol / 760 Torr 4: 40 percent / NaNO2, 3 N H2SO4 / H2O / 0 - 5 °C 5: 35 percent / paraffin / 0.08 h / 330 °C View Scheme
参考文献
Kalinowski, Jerzy; Rykowski, Andrzej; Nantka-Namirski, Pawel
Polish Journal of Chemistry, 1984 , vol. 58, # 1-3 p. 125 - 134
反应条件
1: tris-(dibenzylideneacetone)dipalladium(0); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; caesium carbonate / 1,4-dioxane / 42 h / 110 °C / |Inert atmosphere 2: palladium 10 on activated carbon; ammonium formate / methanol / 2 h / |Reflux View Scheme
参考文献
Wolinska, Ewa
Heterocyclic Communications, 2012 , vol. 18, # 5-6 p. 227 - 232
反应条件
potassium carbonate T=175°C;
参考文献
Polish Journal of Chemistry, , vol. 72, # 11 p. 2378 - 2383
反应条件
potassium carbonate T=170 - 175°C; 0.25 h;
参考文献
Polish Journal of Chemistry, , vol. 72, # 11 p. 2378 - 2383
反应条件
1: concentrated sulfuric acid; peroxomonosulfuric acid View Scheme
参考文献
Brown
Journal of the American Chemical Society, 1957 , vol. 79, p. 3565
