反应条件
1: 4-{4-[(S)-5-[(((4-chlorophenyl)methylene)amino)methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one With hydrogenchloride in water; ethyl acetate T=20°C; 2 h; 2: 5-chloro-2-thiophenecarbonyl chloride With sodium hydroxide in dichloromethane; water T=20°C; pH=7 - 8; 4 h;
参考文献
INTERQUIM, S.A.; Berzosa Rodríguez, Xavier; Marquillas Olondriz, Francisco; Llebaria Soldevilla, Amadeo; Serra Comas, Carme
Patent: US2014/128601 A1, 2014 ;
Location in patent: Paragraph 0068 ;
