2-乙酰氨基-2-脱氧-beta-D-吡喃葡萄糖胺合成路线 （共 6 条）
反应条件
T=4 - 20°C; Inert atmosphere;
参考文献
Orth, Ronald; Pitscheider, Maximilian; Sieber, Stephan A.
Synthesis, 2010 , # 13 art. no. C01710SS, p. 2201 - 2206
反应条件
anhydrous ammonium carbonate
参考文献
Meldal, Morten; Book, Klaus
Tetrahedron Letters, 1990 , vol. 31, # 48 p. 6987 - 6990
反应条件
sodium hydride; lithium bromide in N,N-dimethyl-formamide T=20°C; diastereoselective reaction;
参考文献
Xue, Jun; Kumar, Vipin; Khaja, Sirajud D.; Chandrasekaran; Locke, Robert D.; Matta, Khushi L.
Tetrahedron, 2009 , vol. 65, # 40 p. 8325 - 8335
反应条件
Escherichia coli β-galactosidase T=30°C; pH=7.3; aq. buffer; regioselective reaction;
参考文献
Tetrahedron, , vol. 67, # 40 p. 7708 - 7712
反应条件
1: 2-acetamido-2-deoxy-β-D-glucopyranose; toluene-4-sulfonic acid hydrazide With acetic acid in water; N,N-dimethyl-formamide T=37°C; 24 h; 2: methanol With N-bromosuccinmide in water; N,N-dimethyl-formamide T=0 - 20°C; 0.583333 h;
参考文献
Chibba, Anthony; Poloczek, Joanna; Little, Dustin J.; Howell, P. Lynne; Nitz, Mark
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 35 p. 7103 - 7107
反应条件
1.1: montmorillonite K-10 / 24 h / 0 °C
2.1: trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane / 0.92 h / 50 °C
3.1: copper dichloride / toluene
3.2: 2.25 h / 62 °C / |Sealed tube; |Inert atmosphere
View Scheme
参考文献
Wipf, Peter; Neal, Matthew D.; Chhinder, Sodhi P.; Hackam, David J.
Patent: US2013/281395 A1, 2013 ;
