(E)-3,7-二甲基-2,6-辛二烯醛合成路线 （共 128 条）
反应条件
1: 93 percent / Ag2O, aq. NaOH / 8 h
2: 59 percent / 99percent HCO2H / 0.33 h / Heating
3: 68 percent / K2CO3 / acetone / 24 h / Ambient temperature
4: 81 percent / MCPBA / CH2Cl2 / 1.) 0 deg C, 2 h, 2.) r.t., 2 h
5: 70 percent / NaOMe / methanol / 10 h / Heating
6: 96 percent / CrO3, H2SO4 / acetone
7: 89 percent / NBS / CCl4 / Irradiation
8: 86 percent / NaOMe / methanol; tetrahydrofuran
9: 87 percent / K2CO3 / acetone
10: 51 percent / glac. AcOH, aq. HCl / 5 h / Heating
View Scheme
参考文献
Kadas, Istvan; Arvai, Geza; Horyath, Gabriella
Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 79 - 85
反应条件
1: aq. H2SO4
2: NaBH4
3: PBr3
View Scheme
参考文献
Bhar, Shanta S.; Ramana
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8935 - 8937
反应条件
1: KCN/18-crown-6 complex / CH2Cl2 / 0.25 h / 0 °C
2: pyridinium dichromate / CH2Cl2 / 5 h / 23 °C
View Scheme
参考文献
Corey, E. J.; Schmidt, Greg
Tetrahedron Letters, 1980 , vol. 21, p. 731 - 734
反应条件
manganese(IV) oxide; pyrrolidine; acetic acid in acetonitrile
T=81°C; 8 h;
参考文献
Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung
Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850
反应条件
1: Mg / 1.) ether, 2.) ether, 30 min., reflux
2: 90 percent / VO(acac)2, t-butyl hydroperoxide / benzene; H2O / 4 h / Heating
3: 1.) N-chlorosuccinimide, dimethylsulfide, 2.) triethylamine / 1.) toluene, -25 deg C; 2.) toluene, r.t., 5 min.
View Scheme
参考文献
Sato, Tadashi; Kikuchi, Toshihiro; Tsujita, Hiroshi; Kaetsu, Atsushi; Sootome, Norio; Nishida, Ken-Ichiro; Tachibana, Kazutaka; Murayama, Eigoro
Tetrahedron, 1991 , vol. 47, # 20-21 p. 3281 - 3304
反应条件
1: piperidine
2: NaBH4 / methanol
View Scheme
参考文献
Jacob, L.; Julia, M.; Pfeiffer, B.; Rolando, C.
Tetrahedron Letters, 1983 , vol. 24, # 40 p. 4327 - 4330
反应条件
bei der Zersetzung das Reaktionsprodukt durch Wasser;
参考文献
Harries; Himmelmann
Chemische Berichte, 1907 , vol. 40, p. 2823
反应条件
1.1: 90 percent / n-BuLi / tetrahydrofuran
2.1: 9-BBN / tetrahydrofuran / 4 h / 20 °C
2.2: 77 percent / Cs2CO3; PdCl2(dppf); Ph3As / dimethylformamide / 2.5 h / 50 °C
View Scheme
参考文献
Tago, Keiko; Kogen, Hiroshi
Tetrahedron, 2000 , vol. 56, # 45 p. 8825 - 8831
