N-苯甲酰基-3’-O-(4,4’-二甲氧基三苯甲基)-2’-脱氧胞啶合成路线 （共 4 条）
反应条件
1: in pyridine
T=20°C; 6 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
2 h;
参考文献
Mitsui Chemicals, Inc.
Patent: US2003/229223 A1, 2003 ;
Location in patent: Page 4 ;
反应条件
1: pyridine
2: 1,8-diazabicyclo[5.4.0]undec-7-ene / CH2Cl2
3: tetrabutylammonium fluoride / tetrahydrofuran
View Scheme
参考文献
Rejman, Dominik; Masojidkova, Milena; Rosenberg, Ivan
Nucleosides, Nucleotides and Nucleic Acids, 2004 , vol. 23, # 11 p. 1683 - 1705
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; Yield given;
参考文献
Esipov, Dmitriy S.; Esipova, Olga V.; Korobko, Vyacheslav G.
Nucleosides and Nucleotides, 1998 , vol. 17, # 9-11 p. 1697 - 1704
反应条件
1: pyridine / 16 h / 70 °C
2: sodium methylate / methanol / 16 h / 0 - 20 °C
View Scheme
参考文献
Diaz-Rodriguez, Alba; Fernandez, Susana; Sanghvi, Yogesh S.; Ferrero, Miguel; Gotor, Vicente
Organic Process Research and Development, 2006 , vol. 10, # 3 p. 581 - 587
