1: 61 percent / phenylmethanol / 100 °C 2: 90 percent / NaOAc, PCC/Al2O3 / CH2Cl2 / Heating 3: 95 percent / NaCNBH3, MgSO4 / acetic acid; methanol / Heating 4: 1.) 4N aq. HCl, 2.) H2 / 2.) 10percent Pd/C / 1.) Et2O, MeOH, a) 0 deg C, 30 min, b) RT, overnight, 2.) Et2O, MeOH, RT, 1 atm, 24 h View Scheme

indium(III) chloride in tetrahydrofuran T=25°C; Rearrangement; 0.166667 h;

ammonia; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in water; acetonitrile T=70°C;