1-(2,3-环氧-beta-D-来苏呋喃糖基)尿嘧啶合成路线 （共 7 条）
反应条件
acetic acid T=20°C; 0.5 h;
参考文献
Webb; Mitsuya; Broder
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1475 - 1479
反应条件
aluminum oxide; trimethylsilyl trifluoromethanesulfonate in methanol
参考文献
Ariza, Xavier; Garces, Josep; Vilarrasa, Jaume
Tetrahedron Letters, 1992 , vol. 33, # 28 p. 4069 - 4072
反应条件
1: diphenyl carbonate, NaHCO3 / dimethylformamide / 4 h / 100 °C 2: NaH / paraffin; dimethylsulfoxide / 0.33 h / Ambient temperature View Scheme
参考文献
Ariza, Xavier; Garces, Josep; Vilarrasa, Jaume
Tetrahedron Letters, 1992 , vol. 33, # 28 p. 4069 - 4072
反应条件
sodium hydride in dimethyl sulfoxide; paraffin 0.333333 h; Ambient temperature;
参考文献
Miah, Anwar; Reese, Colin B.; Song, Quanlai; Sturdy, Zoe; Neidle, Stephen; Simpson, Ian J.; Read, Martin; Rayner, Emma
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 19 p. 3277 - 3283
反应条件
1: pyridine / CH2Cl2 / 1) ice-bath, 15 min; 2) 20 deg C, 3 h 2: aq. NaOH / ethanol / 1 h / 60 °C 3: 82 percent / aq. AcOH / 0.5 h / 20 °C View Scheme
参考文献
Webb; Mitsuya; Broder
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1475 - 1479
反应条件
1: 1.) MsCl, pyridine 2.) 1 M NaOH / 1.) RT, 2.) dioxane, RT, 3 h 2: 97 percent / Me3SiOTf, Al2O3 / methanol View Scheme
参考文献
Ariza, Xavier; Garces, Josep; Vilarrasa, Jaume
Tetrahedron Letters, 1992 , vol. 33, # 28 p. 4069 - 4072
反应条件
hydrogen fluoride in 1,4-dioxane T=120°C; 41 h; high pressure;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, # 3 p. 773 - 775
