叔-丁基 4-氨基-2-氟苯甲酸合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate T=30°C; P=22501.8 Torr; 20 h;
参考文献
Marsham; Jackman; Barker; Boyle; Pegg; Wardleworth; Kimbell; O'Connor; Calvert; Hughes
Journal of Medicinal Chemistry, 1995 , vol. 38, # 6 p. 994 - 1004
反应条件
ammonium chloride in ethanol; water
参考文献
Pharmacia and Upjohn Company
Patent: US6239152 B1, 2001 ;
反应条件
1: SOCl2 / CH2Cl2 2: tetrahydrofuran 3: Fe; aq. NH4Cl View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 23 p. 4213 - 4216
反应条件
1: tetrahydrofuran 2: Fe; aq. NH4Cl View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 23 p. 4213 - 4216
反应条件
1: CrO3; AcOH 2: SOCl2 / CH2Cl2 3: tetrahydrofuran 4: Fe; aq. NH4Cl View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 23 p. 4213 - 4216
反应条件
sodium hydrogencarbonate in tetrahydrofuran T=0 - 50°C; 19 h;
参考文献
DR. REDDY'S LABORATORIES LIMITED; DR. REDDY'S LABORATORIES, INC.
Patent: WO2008/143649 A2, 2008 ;
Location in patent: Page/Page column 59-60 ;
