1: With sodium cyanoborohydride; acetic acid in methanol; water T=5 - 20°C; 2 h; 2: With potassium carbonate in methanol; water pH=10 - 11; Product distribution / selectivity;
1: With water; sodium carbonate 2 - 2.5 h; Heating / reflux; 2: With hydrogenchloride in water 4 h; Heating / reflux; 3: With sodium hydroxide in water T=15 - 20°C; pH=9.75 - 10; Product distribution / selectivity;
1: (S)-4-(4-aminobenzyl)-1,3-oxazolidin-2-one With hydrogenchloride; sodium nitrite in water T=0°C; 0.5 h; 2: With Na2S2O5; sodium hydroxide in water T=2 - 60°C; 1.25 h; Heating / reflux; 3: 4-(N,N-dimethylamino)butyraldehyde diethyl acetal With hydrogenchloride; sodium hydroxide more than 3 stages;