7-羟基吡唑并[4,3-d]嘧啶合成路线 （共 7 条）
参考文献
Journal of the American Chemical Society, , vol. 78, p. 2418,2422
反应条件
in 2-ethoxy-ethanol 2 h; Heating; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 57, # 17 p. 4690 - 4696
参考文献
Journal of the American Chemical Society, , vol. 78, p. 2418,2422
反应条件
1: With thionyl chloride; N,N-dimethyl-formamide T=90°C; 1 h; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
Sunesis Pharmaceuticals, Inc.
Patent: US2007/27166 A1, 2007 ;
Location in patent: Page/Page column 84-85 ;
US 20070027166 A1
反应条件
trichlorophosphate in N,N-dimethyl-formamide 12 h; RefluxInert atmosphere;
参考文献
Radi, Marco; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, Mariangela; Schenone, Silvia; Botta, Maurizio
Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5204 - 5206
反应条件
1: pyridine; P2S5 2: aqueous KOH 3: ethanol; NH3 / 200 °C View Scheme
参考文献
Robins et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 2418,2422
反应条件
1: With thionyl chloride; N,N-dimethyl-formamide
T=90°C; 1 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
Sunesis Pharmaceuticals, Inc.
Patent: US2007/27166 A1, 2007 ;
Location in patent: Page/Page column 84-85 ;
US 20070027166 A1
