1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 1.5 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; 0.166667 h; 3: With sodium hydrogencarbonate in tetrahydrofuran; water

n-butyllithium 1) ether, hexane, 2) ether, -30 deg C, 3.5 h; Yield given. Multistep reaction;

sodium periodate; RuCl2(biox)2 in dichloromethane Catalytic oxidation; 10 h; Heating;