3-[3,4-二(乙酰氧基)苯基]丙烯酸合成路线 （共 14 条）
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / 4 h / |Reflux 2: organic base / dichloromethane / 12 h / 20 °C 3: 1-methylguanidine hydrochloride; triethylamine / dichloromethane; methanol / 20 °C / |Inert atmosphere View Scheme
参考文献
Sanderson, J. Thomas; Clabault, Helene; Patton, Cody; Lassalle-Claux, Gregoire; Jean-Francois, Jacques; Pare, Aurelie F.; Hebert, Martin J.G.; Surette, Marc E.; Touaibia, Mohamed
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 7182 - 7193
参考文献
Pacsu; Stieber
Chemische Berichte, 1929 , vol. 62, p. 2977
反应条件
quinoline; copper
T=195°C;
参考文献
Kaelin
Helvetica Chimica Acta, 1947 , vol. 30, p. 2132,2139
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / 4 h / |Reflux
2: organic base / dichloromethane / 12 h / 20 °C
3: 1-methylguanidine hydrochloride; triethylamine / dichloromethane; methanol / 20 °C / |Inert atmosphere
View Scheme
参考文献
Sanderson, J. Thomas; Clabault, Helene; Patton, Cody; Lassalle-Claux, Gregoire; Jean-Francois, Jacques; Pare, Aurelie F.; Hebert, Martin J.G.; Surette, Marc E.; Touaibia, Mohamed
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 7182 - 7193
