3-[3,4-二(乙酰氧基)苯基]丙烯酸合成路线 （共 14 条）
反应条件
pyridine T=0 - 130°C; 6.5 h;
参考文献
RELIANCE LIFE SCIENCES PVT. LTD.
Patent: US2009/215908 A1, 2009 ;
Location in patent: Page/Page column 12 ;
参考文献
Tiemann; Nagai
Chemische Berichte, 1878 , vol. 11, p. 656
Full Text Show Details
Pacsu; Stieber
Chemische Berichte, 1929 , vol. 62, p. 2977
参考文献
Kobzar', A. Ya.
Chemistry of Natural Compounds, 1986 , vol. 22, # 2 p. 224 - 225
Khimiya Prirodnykh Soedinenii, 1986 , # 2 p. 239 - 240
反应条件
Knoevenagel condensation;
参考文献
Yang, Na; Wang, Qing-He; Wang, Wen-Qian; Wang, Jian; Li, Feng; Tan, Shen-Peng; Cheng, Mao-Sheng
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 53 - 56
参考文献
Tiemann; Nagai
Chemische Berichte, 1878 , vol. 11, p. 656
反应条件
1: thionyl chloride 2: pyridine / benzene / 20 °C / Reflux; Inert atmosphere 3: hydrogenchloride; water / tetrahydrofuran / 336 h / 20 °C 4: acetic acid; zinc / 26 h / 20 °C View Scheme
参考文献
Miyamae, Yusaku; Kurisu, Manami; Han, Junkyu; Isoda, Hiroko; Shigemori, Hideyuki
Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 4 p. 502 - 507
反应条件
1: thionyl chloride 2: pyridine / benzene / 20 °C / Reflux; Inert atmosphere 3: hydrogenchloride; water / tetrahydrofuran / 336 h / 20 °C View Scheme
参考文献
Miyamae, Yusaku; Kurisu, Manami; Han, Junkyu; Isoda, Hiroko; Shigemori, Hideyuki
Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 4 p. 502 - 507
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / 4 h / |Reflux 2: organic base / dichloromethane / 12 h / 20 °C 3: 1-methylguanidine hydrochloride; triethylamine / dichloromethane; methanol / 20 °C / |Inert atmosphere View Scheme
参考文献
Sanderson, J. Thomas; Clabault, Helene; Patton, Cody; Lassalle-Claux, Gregoire; Jean-Francois, Jacques; Pare, Aurelie F.; Hebert, Martin J.G.; Surette, Marc E.; Touaibia, Mohamed
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 7182 - 7193
反应条件
1: thionyl chloride 2: pyridine / benzene / 20 °C / Reflux; Inert atmosphere 3: hydrogenchloride; water / tetrahydrofuran / 336 h / 20 °C 4: acetic acid; zinc / 26 h / 20 °C View Scheme
参考文献
Miyamae, Yusaku; Kurisu, Manami; Han, Junkyu; Isoda, Hiroko; Shigemori, Hideyuki
Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 4 p. 502 - 507
反应条件
1: thionyl chloride 2: pyridine / benzene / 20 °C / Reflux; Inert atmosphere 3: hydrogenchloride; water / tetrahydrofuran / 336 h / 20 °C View Scheme
参考文献
Miyamae, Yusaku; Kurisu, Manami; Han, Junkyu; Isoda, Hiroko; Shigemori, Hideyuki
Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 4 p. 502 - 507
