5-溴-苯并[b]噻吩-2-甲醇合成路线 (共 2 条)
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran T=0 - 20°C; 2 h; 2: With water in tetrahydrofuran
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/68991 A1, 2006 ;
Location in patent: Page/Page column 63 ;
反应条件
lithium tri(t-butoxy)aluminum hydride in tetrahydrofuran
参考文献
Mylari; Beyer; Scott; Aldinger; Dee; Siegel; Zembrowski
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 457 - 465