3-环丁基-3-氧代丙酸甲酯合成路线 （共 4 条）
反应条件
1: 2,2-Dimethyl-[1,3]dioxane-4,6-dione; cyclobutanecarbonyl chloride With pyridine in dichloromethane T=20°C; 2 h; 2: methanol in dichloromethane 2 h; Further stages.;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 24 p. 6836 - 6840
反应条件
pyridine in dichloromethane T=0 - 20°C;
参考文献
WO2006/15842 A1, ;
Page/Page column 34 ;
WO 2006/015842 A1
参考文献
WO2010/120854 A1, ;
Page/Page column 124 ;
WO 2010/120854 A1
反应条件
1,1'-carbonyldiimidazole; magnesium chloride in tetrahydrofuran
参考文献
ACS Medicinal Chemistry Letters, , vol. 2, # 2 p. 171 - 176
