4-氧代-1,4-二氢喹啉-3-羧酸合成路线 （共 14 条）
反应条件
1: With sodium hydroxide; water 2 h; Heating / reflux; 2: With hydrogenchloride in water pH=4;
参考文献
US2008/90864 A1, ;
Page/Page column 7 ;
反应条件
potassium hydroxide Heating;
参考文献
Chemical Communications, , # 43 p. 5438 - 5440
反应条件
1: diphenyl ether / Heating 2: 95 percent / aq. KOH / Heating View Scheme
参考文献
Chemical Communications, , # 43 p. 5438 - 5440
反应条件
sodium hydroxide in water T=80°C; Hydrolysis; 0.5 h;
参考文献
Heterocycles, , vol. 51, # 10 p. 2377 - 2384
反应条件
1.1: ethanol / 3 h / 30 - 110 °C / Inert atmosphere 2.1: diphenylether; ethanol / 3.5 h / 228 - 232 °C / Inert atmosphere 3.1: sodium hydroxide; water / ethanol / 16 h / Reflux 3.2: 20 - 25 °C / pH 2 - 3 View Scheme
反应条件
1: 77 percent / tetrahydrofuran; diethyl ether / 20 °C 2: 79 percent / diphenyl ether / 0.5 h / 230 °C 3: 89 percent / NaOH / H2O / 1 h / 60 °C 4: 0.33 h / 180 °C / heating with powdered glass 5: NaOH / H2O / 0.5 h / 80 °C View Scheme
参考文献
Heterocycles, , vol. 51, # 10 p. 2377 - 2384
反应条件
1: 0.33 h / 180 °C / heating with powdered glass 2: NaOH / H2O / 0.5 h / 80 °C View Scheme
参考文献
Heterocycles, , vol. 51, # 10 p. 2377 - 2384
反应条件
1: 89 percent / NaOH / H2O / 1 h / 60 °C 2: 0.33 h / 180 °C / heating with powdered glass 3: NaOH / H2O / 0.5 h / 80 °C View Scheme
参考文献
Heterocycles, , vol. 51, # 10 p. 2377 - 2384
反应条件
1: 79 percent / diphenyl ether / 0.5 h / 230 °C 2: 89 percent / NaOH / H2O / 1 h / 60 °C 3: 0.33 h / 180 °C / heating with powdered glass 4: NaOH / H2O / 0.5 h / 80 °C View Scheme
参考文献
Heterocycles, , vol. 51, # 10 p. 2377 - 2384
