5-溴-7-乙基-2-甲酰基-苯并呋喃合成路线 （共 14 条）
反应条件
1: 80 percent / potassium carbonate, N, N-dimethylformamide / 1.5 h / Heating 2: 49 percent / trifluoroacetic acid / 0.25 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 28, # 5 p. 1395 - 1403
反应条件
1: 1) sodium methylsulfinylmethide / 1) dimethyl sulfoxide, tetrahydrofuran, 0 deg C, 2 min, 2) tetrahydrofuran, 0 deg C, 30 min, then 24 deg C, 1 h 2: hexane; methanol / 14 h / Heating 3: hydrochloric acid / ethanol View Scheme
参考文献
Weerawarna; Guha-Biswas; Nelson
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1395 - 1403
反应条件
1: 1) sodium methylsulfinylmethide / 1) dimethyl sulfoxide, tetrahydrofuran, 0 deg C, 2 min, 2) tetrahydrofuran, 0 deg C, 30 min, then 24 deg C, 1 h
2: hexane; methanol / 14 h / Heating
View Scheme
参考文献
Weerawarna; Guha-Biswas; Nelson
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1395 - 1403
反应条件
1: 1) sodium methylsulfinylmethide / 1) dimethyl sulfoxide, tetrahydrofuran, 0 deg C, 2 min, 2) tetrahydrofuran, 0 deg C, 30 min, then 24 deg C, 1 h
2: hexane; methanol / 14 h / Heating
3: hydrochloric acid / ethanol
4: 93 percent / hydrogen / 5 percent palladium on carbon / ethanol / 0.25 h / 775.7 Torr
View Scheme
参考文献
Weerawarna; Guha-Biswas; Nelson
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1395 - 1403
