α-三甲基硅烷基乙烯基溴合成路线 （共 42 条）
反应条件
1: 1-bromo-1-trimethylsilylethene With tert.-butyl lithium in diethyl ether; pentane
T=-78°C;
2: 1,5-Diphenylpentan-3-one in diethyl ether; pentane
T=0°C;
3: in diethyl ether; N,N-dimethyl-formamide; pentane
T=80°C; Peterson allenation; Further stages.;
参考文献
Tsubouchi, Akira; Kira, Takashiro; Takeda, Takeshi
Synlett, 2006 , # 16 p. 2577 - 2580
反应条件
1: 1.) Mg
2: CrO3 / H2SO4
View Scheme
参考文献
Garratt, Peter J.; Tsotinis, Andrew
Tetrahedron Letters, 1986 , vol. 27, # 24 p. 2761 - 2762
反应条件
1: 1.) Mg, I2, 2.) 2,2'-bipyridyl / 1.) THF, reflux, 2.5 h, 2.) THF, from 50 deg C to 55 deg C, 5 h
2: 60 percent / Jones reagent / acetone / 3 h
View Scheme
参考文献
Amat, Mercedes; Arioli, Federica; Perez, Maria; Molins, Elies; Bosch, Joan
Organic Letters, 2013 , vol. 15, # 10 p. 2470 - 2473
反应条件
(i) tBuLi, Et2O, pentane, (ii) /BRN= 605330/; Multistep reaction;
参考文献
Paquette, Leo A.; Wells, Gregory J.; Horn, Keith A.; Yan, Tu-Hsin
Tetrahedron, 1983 , vol. 39, p. 913 - 924
反应条件
(i) tBuLi, Et2O, pentane, (ii) /BRN= 1753213/; Multistep reaction;
参考文献
Chan,T.H. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1526 - 1532
反应条件
(i) tBuLi, Et2O, pentane, (ii) /BRN= 506060/; Multistep reaction;
参考文献
Chan,T.H. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1526 - 1532
反应条件
1: (i) tBuLi, Et2O, pentane, (ii) /BRN= 605330/
2: pyridine / Heating
View Scheme
参考文献
Chan,T.H. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1526 - 1532
反应条件
1: (i) tBuLi, Et2O, pentane, (ii) /BRN= 1753213/
2: pyridine / Heating
View Scheme
参考文献
Chan,T.H. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 1526 - 1532
反应条件
tetrakis(triphenylphosphine) palladium(0) in benzene
T=80°C; 40 h; Yields of byproduct given;
参考文献
Carpita, Adriano; Rossi, Renzo; Scamuzzi, Barbara
Tetrahedron Letters, 1989 , vol. 30, # 20 p. 2699 - 2702
反应条件
tert.-butyl lithium in tetrahydrofuran
T=-120°C;
参考文献
Ryu, Ilhyong; Hayama, Yoshihiko; Hirai, Akira; Sonoda, Noboru; Orita, Akihiro; Ohe, Kouichi; Murai, Shinji
Journal of the American Chemical Society, 1990 , vol. 112, # 19 p. 7061 - 7063
