7-(2-萘基)-7-氧代庚酸合成路线 （共 3 条）
反应条件
sodium hydroxide in tetrahydrofuran; methanol 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 13 p. 2877 - 2885
反应条件
1.1: Zn; (CH2)Br2; TMSCl / tetrahydrofuran / 16 h / 20 - 60 °C 1.2: CuCN; LiCl / tetrahydrofuran / 0.17 h / 0 °C 1.3: tetrahydrofuran / 3 h / 0 °C 2.1: 1 N aq. NaOH / tetrahydrofuran; methanol / 2 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 13 p. 2877 - 2885
反应条件
1.1: Zn; (CH2)Br2; TMSCl / tetrahydrofuran / 16 h / 20 - 60 °C 1.2: CuCN; LiCl / tetrahydrofuran / 0.17 h / 0 °C 1.3: tetrahydrofuran / 3 h / 0 °C 2.1: 1 N aq. NaOH / tetrahydrofuran; methanol / 2 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 13 p. 2877 - 2885
