N-(叔丁氧羰基)-O-苄基-L-丝氨酸 N-琥珀酰亚胺酯合成路线 (共 4 条)
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 14 h;
参考文献
Ikeuchi, Yoshitaka; Khan, Fareha Zafar; Naoya, Onishi; Masashi, Shiotsuki; Toshio, Masuda; Yoshiyuki, Nishio; Fumio, Sanda
Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 18 p. 3986 - 3993
反应条件
pyridine in acetonitrile T=20°C; 1.5 h; further solvent, base;
参考文献
Il'ina, A. V.; Davidovich, Yu. A.; Rogozhin, S. V.; Moiseenkov, A. M.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984 , vol. 33, p. 1067 - 1070
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984 , # 5 p. 1163 - 1165
反应条件
4-methyl-morpholine in tetrahydrofuran; acetonitrile Ambient temperature;
参考文献
Jaoudai, Mahmoud; Martinez, Jean; Castro, Bertrand
Journal of Organic Chemistry, 1987 , vol. 52, # 12 p. 2364 - 2367
反应条件
sodium tetrahydroborate in tetrahydrofuran T=0 - 20°C;
参考文献
ONO PHARMACEUTICAL CO., LTD.
Patent: EP1481976 A1, 2004 ;
Location in patent: Page 226 ;