1-甲基-1,3-二氢吲哚-2-硫酮合成路线 （共 11 条）
反应条件
triethylamine in benzene 5 h; Irradiation;
参考文献
Helvetica Chimica Acta, , vol. 80, # 2 p. 388 - 397
反应条件
in benzene 5 h; Irradiation;
参考文献
Helvetica Chimica Acta, , vol. 80, # 2 p. 388 - 397
反应条件
1: 1.) NaH / 1.) THF, 2.) THF, 1 h 2: air / methanol / 20 °C View Scheme
参考文献
Rewcastle; Palmer; Dobrusin; Fry; Kraker; Denny
Journal of Medicinal Chemistry, 1994 , vol. 37, # 13 p. 2033 - 2042
反应条件
tetraphosphorus decasulfide; sodium hydrogencarbonate in tetrahydrofuran
T=20°C; 4 h;
参考文献
Pedras, M. Soledade C.; Jha, Mukund
Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1828 - 1834
参考文献
Warner-Lambert
Patent: US5464861 A1, 1995 ;
US 5464861 A
反应条件
in benzene
1.5 h; Heating;
参考文献
Baudin, J.-B.; Bekhazi, M.; Julia, S. A.; Ruel, O.; Jong, R. L. P. de; Brandsma, L.
Synthesis, 1985 , # 10 p. 956 - 958
反应条件
1: 84 percent / hydrazine hydrate / 0.25 h / 90 °C
2: 94 percent / P2S5; NaHCO3 / tetrahydrofuran / 4 h / 20 °C
View Scheme
参考文献
Pedras, M. Soledade C.; Jha, Mukund
Journal of Organic Chemistry, 2005 , vol. 70, # 5 p. 1828 - 1834
反应条件
1: 1.) NaH / 1.) xylene, reflux, 1.5 h, 2.) reflux, 2 h
2: 1 g / phosphorus pentasulfide / toluene / 4 h / Heating
View Scheme
参考文献
Bordwell, Frederick G.; Fried, Herbert E.
Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4218 - 4223
反应条件
1: 62 percent / AlCl3, NaCl / 1.) 140 deg C, 2.) 220 deg C, 5 min
2: 44 percent / P2S5 / dioxane / 0.5 h / Heating
View Scheme
参考文献
Jackson, Anthony N.; Johnston, David K.; Shannon, Patrick V. R.
Journal of Chemical Research, Miniprint, 1988 , # 9 p. 2017 - 2063
反应条件
1: 1.) n-BuLi
View Scheme
参考文献
Rewcastle, Gordon W.; Denny, William A.
Heterocycles, 1994 , vol. 37, # 2 p. 701 - 708
