3,3-双甲基磺酰基-1-苯丙酮合成路线 （共 47 条）
反应条件
1: carbon disulfide; acetophenone With sodium t-butanolate in toluene
T=0°C; 5 h; Inert atmosphere;
2: methyl iodide in methanol; toluene
0.25 h; Reflux;
参考文献
Smyth, Lynette A.; Matthews, Thomas P.; Horton, Peter N.; Hursthouse, Michael B.; Collins, Ian
Tetrahedron, 2010 , vol. 66, # 15 p. 2843 - 2854
反应条件
carbon disulfide; sodium hydride
Multistep reaction;
参考文献
Huang, Zhi-Tang; Zhang, Ping-Cheng
Synthetic Communications, 1990 , vol. 20, # 9 p. 1399 - 1407
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in tetrahydrofuran
T=20°C; 1.5 h; or with irradiation (UV);
参考文献
Lakeev, S. I.; Galin, F. Z.; Tolstikov, G. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989 , vol. 38, # 1.2 p. 202
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989 , vol. 38, # 1 p. 213 - 214
反应条件
sodium hydride in N,N-dimethyl-formamide
T=35 - 40°C; 8 h;
参考文献
Apparao, Satyam; Ila, Hiriyakkanavar; Junjappa, Hirijakkanavar
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2837 - 2844
反应条件
sulfuric acid in dichloromethane
T=20°C; 10 h;
参考文献
Fu, Zhenqian; Wang, Mang; Ma, Yuhui; Liu, Qun; Liu, Jun
Journal of Organic Chemistry, 2008 , vol. 73, # 19 p. 7625 - 7630
反应条件
sodium hydride in N,N-dimethyl-formamide
T=35 - 40°C; 6 h;
参考文献
Apparao, Satyam; Ila, Hiriyakkanavar; Junjappa, Hirijakkanavar
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2837 - 2844
反应条件
sodium hydroxide in benzene
Heating;
参考文献
Spitzner, Roland; Menzel, Manfred; Schroth, Werner
Synthesis, 1982 , # 3 p. 206 - 210
反应条件
sodium hydride in N,N-dimethyl-formamide
8 h;
参考文献
Apparao, Satyam; Ila, Hiriyakkanavar; Junjappa, Hirijakkanavar
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2837 - 2844
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene
T=80°C;
参考文献
Iwasa, Seiji; Yamamoto, Makoto; Furusawa, Atsuko; Kohmoto, Shigeo; Yamada, Kazutoshi
Chemistry Letters, 1991 , # 8 p. 1457 - 1460
反应条件
sulfuric acid in dichloromethane
T=0 - 20°C; 10 h;
参考文献
Liu, Yingjie; Liu, Jingxin; Wang, Mang; Liu, Jun; Liu, Qun
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 14-15 p. 2678 - 2682
