3,3-双甲基磺酰基-1-苯丙酮合成路线 （共 47 条）
反应条件
1: 85 percent / n-BuLi / tetrahydrofuran / Heating 2: 98 percent / POCl3 / 0 - 90 °C 3: 75 percent / Raney-Ni / ethanol / Heating View Scheme
参考文献
Mahata; Venkatesh; Syam Kumar; Ila; Junjappa
Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3966 - 3975
反应条件
ZnCl2*TMEDA; zinc in ethanol 18 h; Heating;
参考文献
Yadav, K. Mallik; Suresh, Joghee R.; Patro, Balaram; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Tetrahedron, 1996 , vol. 52, # 13 p. 4679 - 4686
反应条件
1: NaBH4 / ethanol / 2 h / Heating 2: 1) BF3*Et2O / 1) room temp., 5 min, 2) reflux, 24 h View Scheme
参考文献
Myrboh, Bekington; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5327 - 5332
反应条件
1: 1) n-BuLi / 1) THF, -78 deg C, 0.5h, 2) THF, -78 deg C to RT, 1h 2: orthophosphoric acid / 3 h / 130 °C 3: 85 percent / <(C6H5)3P>2NiCl2 / benzene; diethyl ether / 12 h / 80 °C View Scheme
参考文献
Gupta, Arun K.; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Tetrahedron, 1990 , vol. 46, # 7 p. 2561 - 2572
反应条件
1: 96 percent / tetrahydrofuran / 1) -78 deg C, 0.5 h, 2) -78 deg C to 0 deg C, 1h 2: 82 percent / H3PO4 88percent / 3 h / 130 - 140 °C 3: 65 percent / Raney nickel View Scheme
参考文献
Gupta, Arun K.; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar
Tetrahedron, 1990 , vol. 46, # 7 p. 2561 - 2572
反应条件
piperidine in ethanol 10 h; Heating;
参考文献
Rao, H. Surya Prakash; Sivakumar
Journal of Organic Chemistry, 2006 , vol. 71, # 23 p. 8715 - 8723
反应条件
sodium hydroxide in dimethyl sulfoxide T=50°C; 1 h; Yield given;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 36, # 1 p. 401 - 404
反应条件
potassium carbonate in chloroform 48 h; Ambient temperature;
参考文献
Kakehi, Akikazu; Ito, Suketaka; Ito, Masayoshi; Yotsuya, Toshiaki; Nagata, Kenji
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 5 p. 1432 - 1442
反应条件
1: 92 percent / tetrahydrofuran / 1 h, -70 deg C, than 1 h, r.t. 2: 91 percent / HCl / methanol; H2O / 1 h / Ambient temperature 3: 49 percent / dil. H2SO4 / aq. ethanol / 1.5 h / Heating View Scheme
参考文献
Okazaki, Renji; Negishi, Yoshio; Inamoto, Naoki
Journal of Organic Chemistry, 1984 , vol. 49, # 20 p. 3819 - 3824
反应条件
sodium 1.) THF, 2.) reflux, 1 d; Yield given. Multistep reaction;
参考文献
Huang, Zhi-Tang; Zhang, Ping-Cheng
Synthetic Communications, 1989 , vol. 19, # 17 p. 2999 - 3006
