4,5,6,7-四氢吲哚合成路线 （共 40 条）
反应条件
1: 49 percent / N-chlorosuccinimide / CCl4 / 15 h / Ambient temperature 2: 1.) MeONa, 2.) silica gel 60 / 1.) MeOH, reflux, 3 h, 2.) hexane, EtOAc 3: 88 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 52, # 10 p. 3705 - 3718
反应条件
1: 1.) MeONa, 2.) silica gel 60 / 1.) MeOH, reflux, 3 h, 2.) hexane, EtOAc 2: 88 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 52, # 10 p. 3705 - 3718
反应条件
1.1: 60 percent / triethylamine / dimethylformamide / Heating 2.1: Ce(NH4)2(NO3)6; CaCO3 / ethanol / cooling 2.2: 62 percent / aq. H2SO4 / dioxane / 5 h / 20 °C 3.1: 83 percent / aq. NH4OH / ethanol / 150 °C View Scheme
参考文献
Heterocycles, , vol. 71, # 2 p. 419 - 428
反应条件
1: 1M H2SO4 / H2O / 3 h / Heating 2: 1) ammonium carbonate, 2) KOH / 1) diethylene glycol, 120-130 deg C, 1h, 2) 195 deg C, 3h View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 109, # 4 p. 287 - 297
反应条件
potassium hydroxide in dimethyl sulfoxide T=115°C; 7 h;
参考文献
Mikhaleva, A. I.; Trofimov, B. A.; Vasil'ev, A. N.; Komarova, G. A.; Skorobogatova, V. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 9 p. 920 - 923
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , # 9 p. 1202 - 1204
反应条件
1: methyltriphenoxyphosphonium iodide / acetonitrile / 0.33 h / Ambient temperature 2: t-BuOK / 2-methyl-propan-2-ol / 5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 12 p. 903 - 904
反应条件
1: ammonium hydroxide / 12 h / 150 °C / Sealed tube 2: sodium tetrahydroborate / methanol View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 33, # 1 p. 341 - 343
反应条件
hydroxylamine hydrochloride in water T=60°C; polimerization under various acidic conditions; Product distribution;
参考文献
Trofimov, B.A.; Korostova, S.E.; Mikhaleva, A.I.; Sobenina, L.N.; Vasil'ev, A.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 12 p. 1257 - 1265
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 12 p. 1631 - 1639
反应条件
anhydrous ammonium carbonate; potassium hydroxide 1) diethylene glycol, 120-130 deg C, 1h, 2) 195 deg C, 3h; Yield given. Multistep reaction;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 109, # 4 p. 287 - 297
反应条件
potassium hydroxide in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=140°C; 1 h; various solvents, temp., times and bases; Product distribution;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, # 9 p. 1763 - 1766
Zhurnal Organicheskoi Khimii, , vol. 17, # 9 p. 1977 - 1980
