2-(2,1,3-苯并恶二唑-5-基)乙醇合成路线 （共 6 条）
反应条件
phosphorous acid trimethyl ester in methanol
参考文献
Merck and Co., Inc.
Patent: US5206240 A1, 1993 ;
US 5206240 A
反应条件
phosphorous acid trimethyl ester in methanol
参考文献
Elliott; Selnick; Claremon; Baldwin; Buhrow; Butcher; Habecker; King; Lynch Jr.; Phillips; Ponticello; Radzilowski; Remy; Stein; White; Young
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3973 - 3976
反应条件
1: acetic anhydride, HNO3 2: 1.) KOH, 2.) NaOCl / 1.) MeOH,. 2.) MeOH, water 3: 75 percent / trimethyl phosphite / methanol View Scheme
参考文献
Elliott; Selnick; Claremon; Baldwin; Buhrow; Butcher; Habecker; King; Lynch Jr.; Phillips; Ponticello; Radzilowski; Remy; Stein; White; Young
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3973 - 3976
反应条件
1: 1.) KOH, 2.) NaOCl / 1.) MeOH,. 2.) MeOH, water 2: 75 percent / trimethyl phosphite / methanol View Scheme
参考文献
Elliott; Selnick; Claremon; Baldwin; Buhrow; Butcher; Habecker; King; Lynch Jr.; Phillips; Ponticello; Radzilowski; Remy; Stein; White; Young
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3973 - 3976
反应条件
1: 4-DMAP 2: acetic anhydride, HNO3 3: 1.) KOH, 2.) NaOCl / 1.) MeOH,. 2.) MeOH, water 4: 75 percent / trimethyl phosphite / methanol View Scheme
参考文献
Elliott; Selnick; Claremon; Baldwin; Buhrow; Butcher; Habecker; King; Lynch Jr.; Phillips; Ponticello; Radzilowski; Remy; Stein; White; Young
Journal of Medicinal Chemistry, 1992 , vol. 35, # 21 p. 3973 - 3976
反应条件
triethylamine in dichloromethane
参考文献
Merck and Co., Inc.
Patent: US5112824 A1, 1992 ;
