6,7-二甲氧基-3,4-二氢-2H-1-萘酮合成路线 （共 42 条）
反应条件
trichloro acetic anhydride T=70°C; Friedel Crafts acylation; 0.1 h; Neat (no solvent);
参考文献
Synthetic Communications, , vol. 39, # 15 p. 2664 - 2673
反应条件
acetone in toluene T=80°C; 0.2 h; Flow reactor;
参考文献
Organic Letters, , vol. 15, # 22 p. 5698 - 5701
反应条件
AlCl3, aluminium chloride in dichloromethane T=0 - 20°C; Friedel-Crafts Acylation; Inert atmosphere; regioselective reaction;
参考文献
European Journal of Organic Chemistry, , # 35 p. 6841 - 6845
反应条件
1: H2 / Pd/C / acetic acid / 65 °C 2: PPA / 80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 13 p. 1747 - 1752
反应条件
boron trifluoride diethyl etherate; mercury(II) oxide in tetrahydrofuran; water 7 h;
参考文献
Journal of Organic Chemistry, , vol. 55, # 17 p. 5078 - 5088
反应条件
1: 95 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 20 h / Ambient temperature 2: 95 percent / H2 / Pd/C 3: 93 percent / polyphosphoric acid / 4 h / 40 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 24 p. 4933 - 4938
反应条件
1: H2 / Pd-C / acetic acid 2: LiAlH4 / diethyl ether 3: PBr3 / benzene 4: (i) Mg, Et2O, THF, (ii) /BRN= 1900390/ 5: aq. H3PO4, P2O5 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 9, p. 27 - 29
反应条件
acetic acid T=45°C; 3 h;
参考文献
Asian Journal of Chemistry, , vol. 23, # 3 p. 1117 - 1119
反应条件
1: 76 percent / p-toluenesulfonic acid / acetonitrile / 24 h / 0 °C 2: 60 percent / HgO, aq. THF / BF3.Et2O View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 29 p. 2939 - 2940
反应条件
1: AlCl3 / nitrobenzene / Ambient temperature 2: H2 / Pd/C / acetic acid / 65 °C 3: PPA / 80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 13 p. 1747 - 1752
