1: sodium hydrogencarbonate; water / 1 h / 100 °C 2: acetic anhydride; dimethyl sulfoxide / 24 h / 20 °C View Scheme

sodium hydrogencarbonate; Aliquatreg; 336 in water T=100°C; 1 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '113916', constants.ctx, '0')">N-bromosuccinmide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '984320', constants.ctx, '0')">dibenzoyl peroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098295', constants.ctx, '0')">tetrachloromethane</a> <br />18&nbsp;h;&nbsp;&nbsp;Reflux;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 25 &deg;C<br />2: triethylamine / dichloromethane / 17 h / -5 &deg;C / Inert atmosphere<br />3: N-bromosuccinmide / dibenzoyl peroxide / tetrachloromethane / 18 h / Reflux<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: triethylamine / dichloromethane / 17 h / -5 &deg;C / Inert atmosphere<br />2: N-bromosuccinmide / dibenzoyl peroxide / tetrachloromethane / 18 h / Reflux<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: potassium carbonate / acetone / 4.17 h / 20 &deg;C<br />2: sodium hydride / tetrahydrofuran; mineral oil / 48 h / 25 &deg;C<br />3: triethylamine / dichloromethane / 17 h / -5 &deg;C / Inert atmosphere<br />4: N-bromosuccinmide / dibenzoyl peroxide / tetrachloromethane / 18 h / Reflux<br /> <br /> &nbsp;