1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -70 - -10 °C 2: sulfuric acid / acetonitrile / 3 h / 50 - 60 °C View Scheme

1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -20 - -10 °C 2: hydrogenchloride; water / acetonitrile / 15 h / 40 °C 3: sodium hydroxide; water / ethanol / 16 h / 20 - 25 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1.1: triethylamine / dichloromethane / 2 h / 0 - 10 &deg;C<br />2.1: potassium carbonate / acetonitrile / 70 &deg;C<br />2.2: 15 h / 0 - 25 &deg;C<br /> <br /> &nbsp;

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4267587', constants.ctx, '0')">potassium carbonate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '741857', constants.ctx, '0')">acetonitrile</a> <br />T=70&deg;C;&nbsp;<br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '12147857', constants.ctx, '0')">hexaammonium heptamolybdate tetrahydrate</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587191', constants.ctx, '0')">dihydrogen peroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=0 - 25&deg;C;&nbsp;15&nbsp;h;&nbsp;&nbsp;Product distribution / selectivity;&nbsp;<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: triethylamine / dichloromethane / 1 h / 0 - 5 &deg;C<br />2.1: sodium hydroxide; water / methanol / 40 &deg;C<br />2.2: pH 2 - 4<br />3.1: 1,1'-carbonyldiimidazole / ethyl acetate / 3 h / 0 - 30 &deg;C<br />3.2: 20 - 25 &deg;C<br />4.1: potassium carbonate / acetonitrile / 70 &deg;C<br />4.2: 15 h / 0 - 25 &deg;C<br /> <br /> &nbsp;